NEUROBLASTOMA
Description:
Stores single response data for College of American Pathologists (CAP) form 76035-NEUROBLASTOMA: Resection, Biopsy.

Primary Key
Column Name Ordinal Position
RESULT_ID 1

Column Information
Name Type Discontinued?
1 RESULT_ID VARCHAR No
The unique identifier for the result record.
2 CAP_COMMENTS VARCHAR No
CAP synoptic form item: General comments.
3 SPEC_LATERAL_SPFY VARCHAR No
CAP synoptic form item: Other specimen laterality data.
4 TUMOR_WEIGHT_C_NAME VARCHAR No
CAP synoptic form item: Tumor Weight.
May contain organization-specific values: Yes
Category Entries:
Specify (g)
Cannot be assessed
5 TUMOR_WEIGHT_SPFY NUMERIC No
CAP synoptic form item: Specify Tumor Weight.
6 SPECIMEN_WEIGHT NUMERIC No
CAP synoptic form item: Specimen Weight.
7 SPEC_PROC_SPECIFY VARCHAR No
CAP synoptic form item: Specify the Specimen Procedure.
8 SPEC_SIZE_GREATEST NUMERIC No
CAP synoptic form item: Specimen Greatest Size.
9 SPEC_SIZE_ADDL NUMERIC No
CAP synoptic form item: Specimen size additional dimension (length).
10 SPEC_SIZE_ADDL2 NUMERIC No
CAP synoptic form item: Specimen size additional dimension (width).
11 TUMOR_SIZE_GREAT NUMERIC No
CAP synoptic form item: Tumor Greatest Size.
12 TUMOR_SIZE_ADDL NUMERIC No
CAP synoptic form item: Tumor Size (length).
13 TUMOR_SIZE_ADDL2 NUMERIC No
CAP synoptic form item: Tumor Size (width).
14 TUMOR_SIZE_SPECIFY VARCHAR No
CAP synoptic form item: Specify Tumor Size.
15 SPECIFIC_MARGINS VARCHAR No
CAP synoptic form item: Specific Margins.
16 SPECIMEN_OTHER_SPFY VARCHAR No
CAP synoptic form item: Specify other specimen.
17 REG_LMPH_SITE_SPEC VARCHAR No
CAP synoptic form item: Specify Regional Lymph Nodes Site.
18 REG_LN_NUM_EXM NUMERIC No
CAP synoptic form item: Regional Lymph Nodes Number Examined.
19 REG_LN_NUM_INV NUMERIC No
CAP synoptic form item: Regional Lymph Nodes Number Involved.
20 PRIMARY_TUMOR_C_NAME VARCHAR No
CAP synoptic form item: Primary Tumor (pT).
May contain organization-specific values: Yes
Category Entries:
pTX: Cannot be determined
pTX: Cannot be assessed, or tumor proven by presence of malignant cells in sputum or
pTX: Cannot be assessed
pT0: No evidence of primary tumor
pTis: Carcinoma in situ
pTis (DCIS): Ductal carcinoma in situ
pTis (LCIS): Lobular carcinoma in situ
pTis (Paget): Paget disease of the nipple NOT associated with invasive carcinoma and
pTis: Carcinoma in situ, intraepithelial (no invasion)
pTis: Carcinoma in situ, invasion of lamina propria
pTis: High-grade dysplasia / carcinoma in situ
pTis: Tubal intraepithelial carcinoma (limited to tubal mucosa)
pTis: Melanoma in situ (i.e., not an invasive tumor: anatomic level I)
Encapsulated
Extracapsular extension without adjacent organ involvement
Extension into adjacent organs
Extension into spinal canal
pTa: Papillary noninvasive carcinoma
pTa: Noninvasive papillary carcinoma
pTis: Intratubular germ cell neoplasia only (carcinoma in situ)
pTis: Flat carcinoma in situ
pTis: Carcinoma in situ: flat tumor
Iris
Ciliary Body and Choroid
pT1: Tumor 5 cm or less in greatest dimension, no extra-adrenal invasion
pT1: Tumor limited to ampulla of Vater or sphincter of Oddi
pT1: Tumor 2 cm or less in greatest dimension
pT1: Tumor invades submucosa
pT1: Tumor confined to the bile duct histologically
pT1: Solitary tumor without vascular invasion
pT1: Tmr confined to bile duct, w/ extension up to muscle layer or fibrous tissue
pT1: Tumor 8 cm or less in greatest dimension
pT1mi: Tumor <= 1 mm in greatest dimension (microinvasion)
pT1a: Tumor > 1 mm but <= 5 mm in greatest dimension
pT1b: Tumor > 5 mm but <= 10 mm in greatest dimension
pT1c: Tumor > 10 mm but <= 20 mm in greatest dimension
pT1a (IA): Tumor limited to endometrium or invades less than one-half of myometrium
pT1b (IB): Tumor invades greater than or equal to one-half of the myometrium
pT1: Tumor invades lamina propria, muscularis mucosae, or submucosa
pT1a: Tumor invades lamina propria or muscularis mucosae
pT1a: Tumor invades lamina propria
pT1 (I): Tumor limited to fallopian tube(s)
pT1a (IA): Tumor limited to 1 tube without penetrating serosal surface; no ascites
pT1b (IB): Tumor limited to both tubes w/o penetrating serosal surface; no ascites
pT1c (IC): Tmr limited to 1 or both tube(s) w/ extension into or through tubal serosa
pT1b: Tumor invades submucosa
pT1b: Tumor invades muscle layer
pT1: Tumor 7 cm or less in greatest dimension, limited to the kidney
pT1a: Tumor 4 cm or less in greatest dimension, limited to the kidney
pT1b: Tumor > 4cm but not more than 7cm in greatest dimension, limited to kidney
pT1a: Tumor 2 cm or less in greatest dimension, surrounded by lung or visceral pleura
pT1b: Tumor greater than 2 cm, but 3 cm or less in greatest dimension, surrounded by
pT1: Tumor <=2cm in greatest dimension (without extraparenchymal extension) (Note I)
pT1a: Tumor limited to ipsilateral parietal pleura with or without mediastinal or
pT1b: Tumor involves ipsilateral parietal pleura with or without mediastinal or
pT1a: Melanoma 1.0 mm or less in thickness, no ulceration, <1 mitoses / mm*mm
pT1b: Melanoma 1.0 mm or less in thickness with ulceration and/or 1+ mitoses/mm*mm
pT1a (IA): Tumor limited to one ovary; capsule intact, no tumor on ovarian surface. N
pT1b (IB): Tumor limited to both ovaries; capsule intact, no tumor on ovarian surface
pT1c (IC): Tumor limited to one or both ovaries with any of the following: capsule
pT1: Tumor limited to the pancreas, 2 cm or less in greatest dimension
pN1: Metastasis in a single ipsilateral lymph node, 3 cm or less in greatest dimen
pT1: Tumor confined to nasopharynx, or tumor extends to oropharynx and / or nasal
pT1: Tmr limited to one subsite of hypopharynx and/or 2 cm or less in greatest dimen
pT1: Tumor invades subepithelial connective tissue (lamina propria)
pT1: Tumor confined to the eye with no optic nerve or choroidal invasion
pT1a: Tumor 5 cm or less in greatest dimension, superficial tumor
pT1b: Tumor 5 cm or less in greatest dimension, deep tumor
pT1: Tumor 2 cm or less in greatest dimension with less than two high risk features
pT1: Tumor limited to the testis and epididymis without vascular / lymphatic invasion
pT1: Tumor size 2 cm or less, limited to thyroid
pT1a: Tumor 1 cm or less in greatest dimension limited to the thyroid
pT1b: Tmr more than 1 cm but not more than 2cm in greatest dimen., limited to thyroid
pT1 (I): Tumor confined to uterus
pT1a (IA): Invasive carcinoma diagnosed by microscopy only. All macroscopically
pT1a1 (IA1): Stromal invasion 3.0mm or less in depth, horizontal spread 7.0mm or less
pT1a2 (IA2): Stromal invasion more than 3.0 mm but not more than 5.0 mm in depth
pT1b (IB): Clinically visible lesion confined to cervix/microscopic lesion > T1a2/IA2
pT1b1 (IB1): Clinically visible lesion 4.0 cm or less in greatest dimension
pT1b2 (IB2): Clinically visible lesion more than 4.0 cm in greatest dimension
pT1 (I): Tumor confined to vaginal wall
pT1a (FIGO IA): Lesions 2 cm or less in size, confined to the vulva or perineum
pT1b (FIGO IB): Lesions more than 2 cm in size or any size with stromal invasion more
pT2: Tumor greater than 5 cm, no extra-adrenal invasion
pT2: Tumor invades duodenal wall
pT2: Tumor more than 2 cm but not more than 5 cm in greatest dimension
pT2: Tumor invades muscularis propria
pT2: Tumor invades beyond the wall of the bile duct
pT2a: Solitary tumor with vascular invasion
pT2b: Multiple tumors, with or without vascular invasion
pT2a: Tumor invades beyond the wall of the bile duct to surrounding adipose tissue
pT2b: Tumor invades adjacent hepatic parenchyma
pT2: Tumor more than 8 cm in greatest dimension
pT2: Tumor > 20 mm but <= 50 mm in greatest dimension
pT2 (II): Tumor invades stromal connective tissue of the cervix, but does not extend
pT2 (II): Tumor involves 1 or both tube(s) with pelvic extension
pT2a (IIA): Extension and / or metastasis to the uterus and / or ovaries
pT2b (IIB): Extension to other pelvic structures
pT2c (IIC): Pelvic extension (T2a,T2b/IIA or IIB) w/ malignant cells in ascites
pT2: Tmr invades perimuscular connective tissue; no extension beyond serosa/in liver
pT2: Solitary tumor with vascular invasion or multiple tumors none more than 5 cm
pT2: Tumor more than 7 cm in greatest dimension, limited to the kidney
pT2a: Tumor more than 7 cm but >= 10 cm in greatest dimension, limited to kidney
pT2b: Tumor more than 10 cm, limited to the kidney
pT2: Tumor more than 2 cm but not more than 4 cm in greatest dimension
pT2a: Tumor greater than 3 cm, but 5 cm or less in greatest dimension surrounded by l
pT2b: Tumor greater than 5 cm, but 7 cm or less in greatest dimension
pT2: Tumor >2cm but <=4cm in greatest dimension (without extraparenchymal extension)
pT2: Tumor involves each of the ipsilateral pleural surfaces (parietal, mediastinal,
pT2a: Melanoma 1.01 to 2.0 mm in thickness, no ulceration
pT2b: Melanoma 1.01 to 2.0 mm in thickness, with ulceration
pT2a (IIA): Extension and / or implants on uterus and / or tube(s). No malignant cell
pT2b (IIB): Extension to other pelvic tissues. No malignant cells in ascites or
pT2c (IIC): Pelvic extension and/or implants (T2a or T2b / IIa or IIb) with malignant
pT2: Tumor limited to the pancreas, more than 2 cm in greatest dimension
pN2: Metastasis in a single ipsilateral lymph node, more than 3 cm but not more than
pT2: Tumor with parapharyngeal extension
pT2: Tumor invades more than one subsite of hypopharynx or an adjacent site, or
pT2: Organ confined
pT2a: Unilateral, involving one-half of 1 side or less
pT2b: Unilateral, involving more than one-half of 1 side but not both sides
pT2c: Bilateral disease
pT2a: Tmr invades optic nerve head no extend past lamina or focal choroidal invasion
pT2b: Tmr invades optic nerve head no extend past lamina and focal choroidal invasion
pT2a: Tumor more than 5 cm in greatest dimension, superficial tumor
pT2b: Tumor more than 5 cm in greatest dimension, deep tumor
pT2: Tumor greater than 2 cm in greatest dimension with or without one additional
pT2: Tumor limited to the testis and epididymis with vascular / lymphatic invasion
pT2: Tumor more than 2 cm, but not more than 4 cm, limited to thyroid
pT2 (II): Tumor extends outside of the uterus but is limited to genital structures
pT2a: Tumor invades superficial muscularis propria (inner half)
pT2b: Tumor invades deep muscularis propria (outer half)
pT2a (IIA): Tumor without parametrial invasion
pT2a1 (IIA1): Clinically visible lesion less than or equal to 4.0cm in greatest dimen
pT2a2 (IIA2): Clinically visible lesion greater than 4.0 cm in greatest dimension
pT2b (IIB): Tumor with parametrial invasion
pT2 (II): Tumor invades paravaginal tissues but not the pelvic wall
pT2 (FIGO II): Tumor of any size with extension to adjacent perineal structures
pT3: Tumor of any size with local invasion, but not invading adjacent organs
pT3: Tumor invades pancreas
pT3: Tumor more than 5 cm in greatest dimension
pT3: Tumor invades through the muscularis propria into the subserosa or mesoappendix
pT3: Tmr invades gallbladder,pancreas,duodenum,other adj. organs w/o involvement of
pT3: Tmr perforates visc. peritoneum/invol local extrahepatic struct. by direct invas
pT3: Tumor invades unilateral branches of the portal vein or hepatic artery
pT3: Discontinuous tumors in primary bone site (not including skip metastases)
pT3: Tumor > 50 mm in greatest dimension
pT3: Tumor invades through the muscularis propria into pericolorectal tissues
pT3a (IIIA): Tumor involves serosa and / or adnexa (direct extension or metastasis)
pT3b (IIIB): Vaginal involvement (direct extension/metastasis) or parametrial involve
pT3: Tumor invades adventitia
pT3/N1 (III): Tmr involves 1 or both tube(s) with peritoneal implants outside pelvis
pT3a (IIIA): Microscopic peritoneal metastasis beyond pelvis
pT3b (IIIB): Macroscopic peritoneal metastasis beyond pelvis <=2cm in greatest dimen
pT3c / NI (IIIC): Peritoneal metastasis beyond pelvis >2cm in greatest dimen
pT3: Tumor perforates serosa (visceral peritoneum) and/or directly invades the liver
pT3a: Multiple tumors more than 5 cm
pT3b: Single/multiple tmrs any size involving major branch of portal/hepatic veins
pT3: Tmr extends into major veins/perinephric tissues, not into ipsilateral adrenal
pT3a: Tumor grossly extends into the renal vein or its segmental (muscle containing)
pT3b: Tumor grossly extends into the vena cava below the diaphragm
pT3c: Tmr grossly extends into vena cava above diaphragm or invades wall of vena cava
pT3: Mucosal disease
pT3: Tumor more than 4 cm in greatest dimension
pT3: Tumor greater than 7 cm in greatest dimension; or Tumor of any size that
pT3: Tumor more than 4 cm and / or tumor (having extraparenchymal extension) (Note I)
pT3: Locally advanced but potentially resectable tumor that involves all of the
pT3a: Melanoma 2.01 to 4.0 mm in thickness, no ulceration
pT3b: Melanoma 2.01 to 4.0 mm in thickness, with ulceration
pT3a (IIIA): Microscopic peritoneal metastasis beyond pelvis (no macroscopic tumor)
pT3b (IIIB): Macroscopic peritoneal metastasis beyond pelvis <=2 cm in greatest dimen
pT3c and / or N1 (IIIC): Peritoneal metastasis beyond pelvis >2 cm in greatest dimen
pT3: Tumor extends beyond the pancreas but without involvement of the celiac axis or
pT3: Tmr >4 cm in greatest dimension/extension to lingual surface of epiglottis
pT3: Tumor invades bony structures of skull base and / or paranasal sinuses
pT3: Tumor measures more than 4 cm in greatest dimension or with fixation of hemilary
pT3a: Extraprostatic extension or microscopic invasion of bladder neck
pT3b: Seminal vesicle invasion
pT3: Tumor invades beyond muscularis into peripelvic fat or the renal parenchyma
pT3a: Tumor invades optic nerve past lamina cribrosa OR focal choroidal invasion
pT3b: Tumor invades optic nerve past lamina cribrosa AND focal choroidal invasion
pT3: Tumor invades through the muscularis propria into the subserosa or into the
pT3: Tumor with invasion of maxilla, mandible, orbit, or temporal bone
pT3: Tumor invades subserosal connective tissue, without involvement of
pT3: Tumor invades spermatic cord with or without vascular / lymphatic invasion
pT3: Tumor >4 cm limited to thyroid or any tumor with minimal extrathyroid extension
pT3: Tumor invades beyond muscularis propria into periureteric fat
pT3a: Microscopically
pT3b: Macroscopically (extravesicular mass)
pT3a (IIIA): Tumor involves lower third of vagina, but not pelvic wall
pT3b (IIIB): Tmr extend to pelvic wall and/or causes hydronephrosis/non-funct. kidney
pT3 (III): Tumor extends to pelvic wall
pT3 (FIGO IVA): Tumor of any size with extension to any of the following
pT4: Tumor of any size with invasion of adjacent organs
pT4: Tumor invades peripancreatic soft tissues or other adjacent organs or structures
pT4: Tmr of any size w/ invasion of adjacent organ(s) e.g. vagina, urethra, bladder
pT4: Tumor penetrates visceral peritoneum, including mucinous peritoneal tumor within
pT4: Tumor involves the celiac axis or the superior mesenteric artery
pT4: Tumor with periductal invasion
pT4: Tumor invades main portal vein or its branches bilaterally; or the common hepati
pT4 (IVA): Tumor invades bladder mucosa and/or bowel mucosa
pT4: Tumor invades adjacent structures
pT4: Tumor invades main portal vein or hepatic artery or invades 2+ extrahepatic
pT4: Tmr w/ direct invasion of adj. organs other than gallbladder
pT4: Tmr invades beyond Gerota’s fascia
pT4: Tumor of any size that invades any of the following: mediastinum, heart, great
pT4: Locally advanced technically unresectable tumor involving all of the ipsilateral
pT4: Tumor with intracranial extension and / or involvement of cranial nerves,
pT4: Invasion of rectum, levator muscles, and / or pelvic wall (Note J)
pT4: Tumor invades adjacent organs, or through the kidney into the perinephric fat
pT4a: Tmr invades optic nerve to resection line, no extra-ocular extension identified
pT4b: Tumor invades optic nerve to resection line, extra-ocular extension identified
pT4: Tumor with direct or perineural invasion of skull base or axial skeleton
pT4: Tmr involves visc. peritoneum (serosal surf.) or directly invades adj. structure
pT4: Tumor invades scrotum with or without vascular / lymphatic invasion
pT4: Tumor invades adjacent organs
pT4 (IVA): Tmr invades the mucosa of bladder/rectum and/or extends beyond true pelvis
pT4 (IVA): Tmr invades mucosa of bladder or rectum and/or extends beyond true pelvis
pT4a: Tumor penetrates visceral peritoneum, including mucinous peritoneal tumor withi
pT4a: Tumor penetrates the visceral peritoneum
pT4a: Extension to chest wall, not including only pectoralis muscle adherence / invas
pT4b: Ulceration/ipsilateral satellite nodules/edema of skin which dont meet criteria
pT4c: Both T4a and T4b
pT4d: Inflammatory carcinoma
pT4b: Tumor directly invades other organs or structures
pT4b: Tumor directly invades or is adherent to other organs or structures
pT4a: Resectable tumor invading pleura, pericardium, or diaphragm
pT4b: Unresectable tmr invading other adj. structures, such as aorta, vertebral body
Any T / Any N and M1 (IV): Distant metastasis including presence of malignant cells
Primary Tumor (pT): Supraglottis
Primary Tumor (pT): Glottis
Primary Tumor (pT): Subglottis
pT4a: Moderately advanced disease. Tumor involving deep soft tissue, cartilage, bone,
pT4b: Very advanced disease. Tumor involving brain, dura, skull base,
pT4a: Moderately advanced local disease.
pT4b: Very advanced local disease.
pT4a: Moderately advanced local disease. Tumor invades skin, mandible, ear canal,
pT4b: Very advanced local disease. Tumor invades skull base and / or pterygoid plates
pT4a: Melanoma greater than 4.0 mm in thickness, no ulceration
pT4b: Melanoma greater than 4.0 mm in thickness, with ulceration
Primary Tumor (pT): Maxillary Sinus
Primary Tumor (pT): Nasal Cavity and Ethmoid Sinus
pT4a: Moderately advanced local disease. Tumor invades larynx, deep / extrinsic
pT4b: Very advanced local disease. Tumor invades lateral pterygoid muscle, pterygoid
pT4a: Moderately advanced local disease. Tumor invades thyroid / cricoid cartilage,
pT4b: Very advanced local disease. Tumor invades prevertebral fascia, encases
pT4a: Tumor involves visceral peritoneum (serosal surface)
pT4b: Tumor directly invades adjacent structures
pT4a: Moderately advanced disease. Tumor of any size extending beyond the thyroid
pT4b: Very advanced disease. Tumor invades prevertebral fascia or encases carotid
pT4a: Intrathyroidal anaplastic carcinoma-surgically resectable
pT4b: Extrathyroidal anaplastic carcinoma-surgically unresectable
pT4a: Tumor invades prostatic stroma or uterus or vagina
pT4b: Tumor invades pelvic wall or abdominal wall
Not identified
21 DSTNT_METASTATIS_ST VARCHAR No
CAP synoptic form item: Distant Metastasis Sites.
22 ADDL_PATH_FIND_SPFY VARCHAR No
CAP synoptic form item: Specify additional pathologic findings.
23 PATIENT_AGE_C_NAME VARCHAR No
CAP synoptic form item: Patient Age.
May contain organization-specific values: Yes
Category Entries:
Not specified
<18 months
>= 18 months and <5 years
>= 5 years
24 TREATMENT_HISTORY_C_NAME VARCHAR No
CAP synoptic form item: Treatment History.
May contain organization-specific values: Yes
Category Entries:
No known presurgical chemotherapy
Presurgical chemotherapy given
Not specified
25 HIST_TYP_GANGLNBL_C_NAME VARCHAR No
CAP synoptic form item: Histologic Type Ganglioneuroblastoma.
May contain organization-specific values: Yes
Category Entries:
Nodular subtype
Intermixed subtype
26 NUM_NODULES_SPFY NUMERIC No
CAP synoptic form item: Nodular Subtype - Specify Number of Nodules.
27 DEG_DIFFERENTIAT_C_NAME VARCHAR No
CAP synoptic form item: Degree of Differentiation (neuroblastic component).
May contain organization-specific values: Yes
Category Entries:
Undifferentiated
Poorly differentiated
Differentiating
Cannot be assessed
Not applicable
28 MITOTC_KARY_INDEX_C_NAME VARCHAR No
CAP synoptic form item: Mitotic-Karyorrhectic Index (MKI).
May contain organization-specific values: Yes
Category Entries:
Low (<100 per 5000 cells; <2%)
Intermediate (100-200 per 5000 cells; 2%-4%)
High (>200 per 5000 cells; >4%)
Indeterminate
Cannot be assessed
Not applicable
29 TMR_CALCIFICATION_C_NAME VARCHAR No
CAP synoptic form item: Tumor Calcification.
May contain organization-specific values: Yes
Category Entries:
Cannot be assessed
Not identified
Absent
Present
Indeterminate
Portal vein invasion present
Hepatic vein invasion present
Present within tumor nodules
Present in vessels of parenchyma outside of tumor nodules
Cannot be determined
30 INPC_C_NAME VARCHAR No
CAP synoptic form item: International Neuroblastoma Pathology Classification (INPC).
May contain organization-specific values: Yes
Category Entries:
Favorable histopathology
Unfavorable histopathology
Not applicable secondary to previous chemotherapy
Cannot be determined secondary to insufficient material
Indeterminate
31 INSS_C_NAME VARCHAR No
CAP synoptic form item: International Neuroblastoma Staging System (INSS).
May contain organization-specific values: Yes
Category Entries:
Stage 1
Stage 2A
Stage 2B
Stage 3
Stage 4
Stage 4S
32 MYCN_AMPLIF_STATS_C_NAME VARCHAR No
CAP synoptic form item: MYCN Amplification Status.
May contain organization-specific values: Yes
Category Entries:
Not assessed
Not amplified
Amplified
Gain
Indeterminate
33 DIST_META_NON_PM_C_NAME VARCHAR No
CAP synoptic form item: Distant Metastasis (non-pM).
May contain organization-specific values: Yes
Category Entries:
Cannot be assessed
Not Applicable
Distant Metastasis
34 REG_LYM_ND_NON_PN_C_NAME VARCHAR No
CAP synoptic form item: Regional Lymph Nodes (Non pN version).
May contain organization-specific values: Yes
Category Entries:
Cannot be assessed
Regional lymph node metastasis not identified
Regional lymph node metastasis present